Michael L. Metzker, Ph.D
Wu, W, Stupi, BP, Litosh, VA, Mansouri, D, Farley, D, Morris, S, Metzker, S, Metzker, ML. Termination of DNA synthesis by N6-alkylated, not 3'-O-alkylated, photocleavable 2'-deoxyadenosine triphosphates. Nucleic Acids Res. 2007; 35(19):6339-49. [PubMed]
Muzny, DM, Scherer, SE, Kaul, R, Wang, J, Yu, J, Sudbrak, R, Buhay, CJ, Chen, R, Cree, A et al. The DNA sequence, annotation and analysis of human chromosome 3. Nature 2006 Apr 27; 440(7088):1194-8. [PubMed]
Scherer, SE, Muzny, DM, Buhay, CJ, Chen, R, Cree, A, Ding, Y, Dugan-Rocha, S, Gill, R, Gunaratne, P et al. The finished DNA sequence of human chromosome 12. Nature 2006 Mar 16; 440(7082):346-51. [PubMed]
Fernandez-Valdivia, R, Zhang, Y, Pai, S, Metzker, ML, Schumacher, A. l7Rn6 encodes a novel protein required for clara cell function in mouse lung development. Genetics 2006 Jan; 172(1):389-99. [PubMed]
Metzker, ML. Emerging technologies in DNA sequencing. Genome Res. 2005 Dec; 15(12):1767-76. [PubMed]
Lewis, EK, Haaland, WC, Nguyen, F, Heller, DA, Allen, MJ, MacGregor, RR, Berger, CS, Willingham, B, Burns, LA et al. Color-blind fluorescence detection for four-color DNA sequencing. Proc. Natl. Acad. Sci. U.S.A. 2005 Apr 12; 102(15):5346-51. [PubMed]
Ross, MT, Grafham, DV, Coffey, AJ, Scherer, S, McLay, K, Muzny, D, Platzer, M, Howell, GR, Burrows, C et al. The DNA sequence of the human X chromosome. Nature 2005 Mar 17; 434(7031):325-37. [PubMed]
Richards, S, Liu, Y, Bettencourt, BR, Hradecky, P, Letovsky, S, Nielsen, R, Thornton, K, Hubisz, MJ, Chen, R et al. Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. Genome Res. 2005 Jan; 15(1):1-18. [PubMed]
Gibbs, RA, Weinstock, GM, Metzker, ML, Muzny, DM, Sodergren, EJ, Scherer, S, Scott, G, Steffen, D, Worley, KC et al. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature 2004 Apr 1; 428(6982):493-521. [PubMed]
Thoresen, LH, Jiao, GS, Haaland, WC, Metzker, ML, Burgess, K. Rigid, conjugated, fluoresceinated thymidine triphosphates: syntheses and polymerase mediated incorporation into DNA analogues. Chemistry (Weinheim an der Bergstrasse, Germany) 2003 Oct 6; 9(19):4603-10. [PubMed]
Ueda, H, Howson, JM, Esposito, L, Heward, J, Snook, H, Chamberlain, G, Rainbow, DB, Hunter, KM, Smith, AN et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003 May 29; 423(6939):506-11. [PubMed]
Twells, RC, Mein, CA, Phillips, MS, Hess, JF, Veijola, R, Gilbey, M, Bright, M, Metzker, M, Lie, BA et al. Haplotype structure, LD blocks, and uneven recombination within the LRP5 gene. Genome Res. 2003 May; 13(5):845-55. [PubMed]
Metzker, ML, Mindell, DP, Liu, XM, Ptak, RG, Gibbs, RA, Hillis, DM. Molecular evidence of HIV-1 transmission in a criminal case. Proc. Natl. Acad. Sci. U.S.A. 2002 Oct 29; 99(22):14292-7. [PubMed]
Dederich, DA, Okwuonu, G, Garner, T, Denn, A, Sutton, A, Escotto, M, Martindale, A, Delgado, O, Muzny, DM et al. Glass bead purification of plasmid template DNA for high throughput sequencing of mammalian genomes. Nucleic Acids Res. 2002 Apr 1; 30(7):e32. [PubMed]
Lander, ES, Linton, LM, Birren, B, Nusbaum, C, Zody, MC, Baldwin, J, Devon, K, Dewar, K, Doyle, M et al. Initial sequencing and analysis of the human genome. Nature 2001 Feb 15; 409(6822):860-921. [PubMed]
Bouck, JB, Metzker, ML, Gibbs, RA. Shotgun sample sequence comparisons between mouse and human genomes. Nat. Genet. 2000 May; 25(1):31-3. [PubMed]
Muzny, DM, Metzker, ML, Bouck, J, Gorrell, JH, Ding, Y, Maxim, E, Gibbs, RA. Using BODIPY dye-primer chemistry in large-scale sequencing. IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society ; 17(6):88-93. [PubMed]
Metzker, ML, Raghavachari, R, Burgess, K, Gibbs, RA. Elimination of residual natural nucleotides from 3'-O-modified-dNTP syntheses by enzymatic mop-up. BioTechniques 1998 Nov; 25(5):814-7. [PubMed]
Metzker, ML, Ansari-Lari, MA, Liu, XM, Holder, DJ, Gibbs, RA. Quantitation of mixed-base populations of HIV-1 variants by automated DNA sequencing with BODIPY dye-labeled primers. BioTechniques 1998 Sep; 25(3):446-7, 450-2, 454, passim. [PubMed]
Ansari-Lari, MA, Liu, XM, Metzker, ML, Rut, AR, Gibbs, RA. The extent of genetic variation in the CCR5 gene. Nat. Genet. 1997 Jul; 16(3):221-2. [PubMed]
Metzker, ML, Lu, J, Gibbs, RA. Electrophoretically uniform fluorescent dyes for automated DNA sequencing. Science 1996 Mar 8; 271(5254):1420-2. [PubMed]
Metzker, ML, Allain, KM, Gibbs, RA. Accurate determination of DNA in agarose gels using the novel algorithm GelScann(1.0). Comput. Appl. Biosci. 1995 Apr; 11(2):187-94. [PubMed]
Metzker, ML, Raghavachari, R, Richards, S, Jacutin, SE, Civitello, A, Burgess, K, Gibbs, RA. Termination of DNA synthesis by novel 3'-modified-deoxyribonucleoside 5'-triphosphates. Nucleic Acids Res. 1994 Oct 11; 22(20):4259-67. [PubMed]