Acorn Worm Genome Project
Photo by Chris Lowe
About the Project
The BCM-HGSC is sequencing the genome of the acorn worm (Saccoglossus kowalevskii). The acorn worm is a hemichordate on a branch of the evolutionary tree between chordates (vertebrates and sea squirt) and echinoderms (sea urchin). The genome sequence is expected to yield insights about evolution, including the origin of chordates, the origin of deuterostomes and the origin of bilateral animals.
The acorn worm Genome Sequencing Consortium is led by the BCM-HGSC. The goal of the project is to produce a six-fold WGS shotgun draft assembly.
An introductory meeting of the acorn worm genome project was held at the BCM-HGSC in 2005 with John Gerhart, Christopher Lowe, and Marc Kirschner. The research community has constructed the following resources:
a 13x coverage 130kb BAC library
three cDNA libraries from different developmental stages
EST data representing ~20,000 unique genes
Access to the Data
A draft assembly (Skow_1.0) is available for download on our FTP site.
The Skow_1.0 assembly covers 90-97% (EST-cDNA representation) of the ~800 Mb genome.
BLAST searches of the Acorn Worm preliminary assembly are now available from our BLAST site. Contig sequences are available from the links in the BLAST output and from the FTP site.