David Nelson, Ph.D.

Tribolium Genome Sequencing Consortium, Richards, S, Gibbs, RA, Weinstock, GM, Brown, SJ, Denell, R, Beeman, RW, Gibbs, R, Beeman, RW et al. The genome of the model beetle and pest Tribolium castaneum.  Nature  2008 Apr 24; 452(7190):949-55. [PubMed]

Rhesus Macaque Genome Sequencing and Analysis Consortium, Gibbs, RA, Rogers, J, Katze, MG, Bumgarner, R, Weinstock, GM, Mardis, ER, Remington, KA, Strausberg, RL et al. Evolutionary and biomedical insights from the rhesus macaque genome.  Science  2007 Apr 13; 316(5822):222-34. [PubMed]

Muzny, DM, Scherer, SE, Kaul, R, Wang, J, Yu, J, Sudbrak, R, Buhay, CJ, Chen, R, Cree, A et al. The DNA sequence, annotation and analysis of human chromosome 3.  Nature  2006 Apr 27; 440(7088):1194-8. [PubMed]

Scherer, SE, Muzny, DM, Buhay, CJ, Chen, R, Cree, A, Ding, Y, Dugan-Rocha, S, Gill, R, Gunaratne, P et al. The finished DNA sequence of human chromosome 12.  Nature  2006 Mar 16; 440(7082):346-51. [PubMed]

Mientjes, EJ, Nieuwenhuizen, I, Kirkpatrick, L, Zu, T, Hoogeveen-Westerveld, M, Severijnen, L, Rife, M, Willemsen, R, Nelson, DL et al. The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo.  Neurobiol. Dis.  2006 Mar; 21(3):549-55. [PubMed]

Yu, F, Sabeti, PC, Hardenbol, P, Fu, Q, Fry, B, Lu, X, Ghose, S, Vega, R, Perez, A et al. Positive selection of a pre-expansion CAG repeat of the human SCA2 gene.  PLoS Genet.  2005 Sep; 1(3):e41. [PubMed]

Koekkoek, SK, Yamaguchi, K, Milojkovic, BA, Dortland, BR, Ruigrok, TJ, Maex, R, De Graaf, W, Smit, AE, VanderWerf, F et al. Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in Fragile X syndrome.  Neuron  2005 Aug 4; 47(3):339-52. [PubMed]

Ross, MT, Grafham, DV, Coffey, AJ, Scherer, S, McLay, K, Muzny, D, Platzer, M, Howell, GR, Burrows, C et al. The DNA sequence of the human X chromosome.  Nature  2005 Mar 17; 434(7031):325-37. [PubMed]

Nelson, DL, Gibbs, RA. Genetics. The critical region in trisomy 21.  Science  2004 Oct 22; 306(5696):619-21. [PubMed]

Mientjes, EJ, Willemsen, R, Kirkpatrick, LL, Nieuwenhuizen, IM, Hoogeveen-Westerveld, M, Verweij, M, Reis, S, Bardoni, B, Hoogeveen, AT et al. Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo.  Hum. Mol. Genet.  2004 Jul 1; 13(13):1291-302. [PubMed]

Matsuura, T, Fang, P, Lin, X, Khajavi, M, Tsuji, K, Rasmussen, A, Grewal, RP, Achari, M, Alonso, ME et al. Somatic and germline instability of the ATTCT repeat in spinocerebellar ataxia type 10.  Am. J. Hum. Genet.  2004 Jun; 74(6):1216-24. [PubMed]

Jin, P, Zarnescu, DC, Ceman, S, Nakamoto, M, Mowrey, J, Jongens, TA, Nelson, DL, Moses, K, Warren, ST. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway.  Nat. Neurosci.  2004 Feb; 7(2):113-7. [PubMed]

Gu, Y, Nelson, DL. FMR2 function: insight from a mouse knockout model.  Cytogenet. Genome Res.  2003; 100(1-4):129-39. [PubMed]

Gibbs, RA, Nelson, DL. Human genetics. Primate shadow play.  Science  2003 Feb 28; 299(5611):1331-3. [PubMed]

Bonnen, PE, Wang, PJ, Kimmel, M, Chakraborty, R, Nelson, DL. Haplotype and linkage disequilibrium architecture for human cancer-associated genes.  Genome Res.  2002 Dec; 12(12):1846-53. [PubMed]

Lander, ES, Linton, LM, Birren, B, Nusbaum, C, Zody, MC, Baldwin, J, Devon, K, Dewar, K, Doyle, M et al. Initial sequencing and analysis of the human genome.  Nature  2001 Feb 15; 409(6822):860-921. [PubMed]

Bonnen, PE, Story, MD, Ashorn, CL, Buchholz, TA, Weil, MM, Nelson, DL. Haplotypes at ATM identify coding-sequence variation and indicate a region of extensive linkage disequilibrium.  Am. J. Hum. Genet.  2000 Dec; 67(6):1437-51. [PubMed]

Adams, MD, Celniker, SE, Holt, RA, Evans, CA, Gocayne, JD, Amanatides, PG, Scherer, SE, Li, PW, Hoskins, RA et al. The genome sequence of Drosophila melanogaster.  Science  2000 Mar 24; 287(5461):2185-95. [PubMed]

Timms, KM, Bondeson, ML, Ansari-Lari, MA, Lagerstedt, K, Muzny, DM, Dugan-Rocha, SP, Nelson, DL, Pettersson, U, Gibbs, RA. Molecular and phenotypic variation in patients with severe Hunter syndrome.  Hum. Mol. Genet.  1997 Mar; 6(3):479-86. [PubMed]

Eichler, EE, Lu, F, Shen, Y, Antonacci, R, Jurecic, V, Doggett, NA, Moyzis, RK, Baldini, A, Gibbs, RA et al. Duplication of a gene-rich cluster between 16p11.1 and Xq28: a novel pericentromeric-directed mechanism for paralogous genome evolution.  Hum. Mol. Genet.  1996 Jul; 5(7):899-912. [PubMed]

Timms, KM, Lu, F, Shen, Y, Pierson, CA, Muzny, DM, Gu, Y, Nelson, DL, Gibbs, RA. 130 kb of DNA sequence reveals two new genes and a regional duplication distal to the human iduronate-2-sulfate sulfatase locus.  Genome Res.  1995 Aug; 5(1):71-8. [PubMed]

Gu, Y, Shen, Y, Gibbs, RA, Nelson, DL. Identification of FMR2, a novel gene associated with the FRAXE CCG repeat and CpG island.  Nat. Genet.  1996 May; 13(1):109-13. [PubMed]

Eichler, EE, Richards, S, Gibbs, RA, Nelson, DL. Fine structure of the human FMR1 gene.  Hum. Mol. Genet.  1993 Aug; 2(8):1147-53. [PubMed]

Nelson, DL, Ballabio, A, Victoria, MF, Pieretti, M, Bies, RD, Gibbs, RA, Maley, JA, Chinault, AC, Webster, TD et al. Alu-primed polymerase chain reaction for regional assignment of 110 yeast artificial chromosome clones from the human X chromosome: identification of clones associated with a disease locus.  Proc. Natl. Acad. Sci. U.S.A.  1991 Jul 15; 88(14):6157-61. [PubMed]