Drosophila modENCODE Project

About the project

Drosophila melanogaster: male and female
D. melanogaster
Male (left) and female

Source: Wikipedia

Links

The modENCODE Project

BCM-HGSC Raw RNAseq Data

BCM-HGSC BLAST

D. biarmipes

D. bipectinata

D. elegans

D. eugracilis

D. ficusphila

D. kikkawai

D. takahashii

D. rhopaloa

 

As part of the Drosophila modENCODE project, we are studying the comparative genomics of eight additional species of Drosophila: biarmipes, bipectinata, elegans, eugracillis, ficusphila, kikkawai, rhopaloa, and takahashii.

Papers:

The aim is to better identify and annotate conserved sequences within the Drosophila genome.

The modEncode comparative genomics white paper also requests the sequencing of the Oregon R fly strain used for many of the modEncode lab experiments.

We sequenced isolates of the strains used in three modENCODE laboratories (Bloomington, Elgin laboratory, Orr-Weaver laboratory) using an illumina re-sequencing approach.

Access to the Data

Eight genome assemblies are now available on the NCBI website.

  1. D. biarmipes

  2. D. bipectinata

  3. D. elegans

  4. D. eugracilis

  5. D. ficusphila

  6. D. kikkawai

  7. D. takahashii

  8. D. rhopaloa

Resources

Raw RNAseq data is available here. This includes sampling from adult males, adult females and mixed embryos for each of the eight species.

Raw sequence reads can be found here. This includes BAM alignment files, and vcf files with SNP and indel calls.

modENCODE Comparative Genomics white paper

Flybase

Genetic Basis of a Violation of Dollo’s Law: Re-Evolution of Rotating Sex Combs in Drosophila bipectinata

NCBI

Listserve

Updates about the modENCODE genome sequencing are being posted to the modENCODE genomics listserv. Please contact Stephen Richards with your email address to sign up.