Preethi H. Gunaratne, Ph.D.

Polikepahad, S, Knight, JM, Naghavi, AO, Oplt, T, Creighton, CJ, Shaw, C, Benham, AL, Kim, J, Soibam, B et al. Proinflammatory role for let-7 microRNAS in experimental asthma.  J. Biol. Chem.  2010 Sep 24; 285(39):30139-49. [PubMed]

Dejosez, M, Levine, SS, Frampton, GM, Whyte, WA, Stratton, SA, Barton, MC, Gunaratne, PH, Young, RA, Zwaka, TP. Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells.  Genes Dev.  2010 Jul 15; 24(14):1479-84. [PubMed]

Zhu, H, Gunaratne, PH, Roman, GW, Gunaratne, GH. A theory for the arrangement of sensory organs in Drosophila.  Chaos  2010 Mar; 20(1):013132. [PubMed]

Warren, WC, Clayton, DF, Ellegren, H, Arnold, AP, Hillier, LW, Kunstner, A, Searle, S, White, S, Vilella, AJ et al. The genome of a songbird.  Nature  2010 Apr 1; 464(7289):757-62. [PubMed]

Creighton, CJ, Benham, AL, Zhu, H, Khan, MF, Reid, JG, Nagaraja, AK, Fountain, MD, Dziadek, O, Han, D et al. Discovery of novel microRNAs in female reproductive tract using next generation sequencing.  PLoS ONE  2010; 5(3):e9637. [PubMed]

Creighton, CJ, Fountain, MD, Yu, Z, Nagaraja, AK, Zhu, H, Khan, M, Olokpa, E, Zariff, A, Gunaratne, PH et al. Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers.  Cancer Res.  2010 Mar 1; 70(5):1906-15. [PubMed]

Greene, SB, Gunaratne, PH, Hammond, SM, Rosen, JM. A putative role for microRNA-205 in mammary epithelial cell progenitors.  J. Cell. Sci.  2010 Feb 15; 123(Pt 4):606-18. [PubMed]

Nagaraja, AK, Creighton, CJ, Yu, Z, Zhu, H, Gunaratne, PH, Reid, JG, Olokpa, E, Itamochi, H, Ueno, NT et al. A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer.  Mol. Endocrinol.  2010 Feb; 24(2):447-63. [PubMed]

MGC Project Team, Temple, G, Gerhard, DS, Rasooly, R, Feingold, EA, Good, PJ, Robinson, C, Mandich, A, Derge, JG et al. The completion of the Mammalian Gene Collection (MGC).  Genome Res.  2009 Dec; 19(12):2324-33. [PubMed]

Wang, Y, Brahmakshatriya, V, Zhu, H, Lupiani, B, Reddy, SM, Yoon, BJ, Gunaratne, PH, Kim, JH, Chen, R et al. Identification of differentially expressed miRNAs in chicken lung and trachea with avian influenza virus infection by a deep sequencing approach.  BMC Genomics  2009; 10():512. [PubMed]

Gunaratne, PH. Embryonic stem cell microRNAs: defining factors in induced pluripotent (iPS) and cancer (CSC) stem cells?  Curr Stem Cell Res Ther  2009 Sep; 4(3):168-77. [PubMed]

Wang, X, Sutton, VR, Eble, TN, Lewis, RA, Gunaratne, P, Patel, A, Van den Veyver, IB. A genome-wide screen for copy number alterations in Aicardi syndrome.  Am. J. Med. Genet. A  2009 Oct; 149A(10):2113-21. [PubMed]

Ma, L, Buchold, GM, Greenbaum, MP, Roy, A, Burns, KH, Zhu, H, Han, DY, Harris, RA, Coarfa, C et al. GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline.  PLoS Genet.  2009 Sep; 5(9):e1000635. [PubMed]

Creighton, CJ, Reid, JG, Gunaratne, PH. Expression profiling of microRNAs by deep sequencing.  Brief. Bioinformatics  2009 Sep; 10(5):490-7. [PubMed]

Lopez-Terrada, D, Gunaratne, PH, Adesina, AM, Pulliam, J, Hoang, DM, Nguyen, Y, Mistretta, TA, Margolin, J, Finegold, MJ. Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors.  Hum. Pathol.  2009 Jun; 40(6):783-94. [PubMed]

Adesina, AM, Lopez-Terrada, D, Wong, KK, Gunaratne, P, Nguyen, Y, Pulliam, J, Margolin, J, Finegold, MJ. Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathways.  Hum. Pathol.  2009 Jun; 40(6):843-53. [PubMed]

Creighton, CJ, Nagaraja, AK, Hanash, SM, Matzuk, MM, Gunaratne, PH. A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions.  RNA  2008 Nov; 14(11):2290-6. [PubMed]

Nagaraja, AK, Andreu-Vieyra, C, Franco, HL, Ma, L, Chen, R, Han, DY, Zhu, H, Agno, JE, Gunaratne, PH et al. Deletion of Dicer in somatic cells of the female reproductive tract causes sterility.  Mol. Endocrinol.  2008 Oct; 22(10):2336-52. [PubMed]

Gu, P, Reid, JG, Gao, X, Shaw, CA, Creighton, C, Tran, PL, Zhou, X, Drabek, RB, Steffen, DL et al. Novel microRNA candidates and miRNA-mRNA pairs in embryonic stem (ES) cells.  PLoS ONE  2008; 3(7):e2548. [PubMed]

Muzny, DM, Scherer, SE, Kaul, R, Wang, J, Yu, J, Sudbrak, R, Buhay, CJ, Chen, R, Cree, A et al. The DNA sequence, annotation and analysis of human chromosome 3.  Nature  2006 Apr 27; 440(7088):1194-8. [PubMed]

Bowman, TV, McCooey, AJ, Merchant, AA, Ramos, CA, Fonseca, P, Poindexter, A, Bradfute, SB, Oliveira, DM, Green, R et al. Differential mRNA processing in hematopoietic stem cells.  Stem Cells  2006 Mar; 24(3):662-70. [PubMed]

Scherer, SE, Muzny, DM, Buhay, CJ, Chen, R, Cree, A, Ding, Y, Dugan-Rocha, S, Gill, R, Gunaratne, P et al. The finished DNA sequence of human chromosome 12.  Nature  2006 Mar 16; 440(7082):346-51. [PubMed]

Al-Lamki, Z, Wali, YA, Wasifuddin, SM, Zachariah, M, Al-Mjeni, R, Li, C, Muralitharan, S, Al-Kharusi, K, Gunaratne, P et al. Identification of prognosis markers in pediatric high-risk acute lymphoblastic leukemia.  Pediatric hematology and oncology  ; 22(7):629-43. [PubMed]

Ross, MT, Grafham, DV, Coffey, AJ, Scherer, S, McLay, K, Muzny, D, Platzer, M, Howell, GR, Burrows, C et al. The DNA sequence of the human X chromosome.  Nature  2005 Mar 17; 434(7031):325-37. [PubMed]

Gunaratne, PH. Advances in genome biology and technology.  Expert Rev. Mol. Diagn.  2004 Nov; 4(6):757-60. [PubMed]

Gerhard, DS, Wagner, L, Feingold, EA, Shenmen, CM, Grouse, LH, Schuler, G, Klein, SL, Old, S, Rasooly, R et al. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).  Genome Res.  2004 Oct; 14(10B):2121-7. [PubMed]

Wu, JQ, Garcia, AM, Hulyk, S, Sneed, A, Kowis, C, Yuan, Y, Steffen, D, McPherson, JD, Gunaratne, PH et al. Large-scale RT-PCR recovery of full-length cDNA clones.  BioTechniques  2004 Apr; 36(4):690-6, 698-700. [PubMed]

Gunaratne, PH, Wu, JQ, Garcia, AM, Hulyk, S, Worley, KC, Margolin, JF, Gibbs, RA. Concatenation cDNA sequencing for transcriptome analysis.  C. R. Biol.  ; 326(10-11):971-7. [PubMed]

Qiu, J, Gunaratne, P, Peterson, LE, Khurana, D, Walsham, N, Loulseged, H, Karni, RJ, Roussel, E, Gibbs, RA et al. Novel potential ALL low-risk markers revealed by gene expression profiling with new high-throughput SSH-CCS-PCR.  Leukemia  2003 Sep; 17(9):1891-900. [PubMed]

Strausberg, RL, Feingold, EA, Grouse, LH, Derge, JG, Klausner, RD, Collins, FS, Wagner, L, Shenmen, CM, Schuler, GD et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.  Proc. Natl. Acad. Sci. U.S.A.  2002 Dec 24; 99(26):16899-903. [PubMed]