Selected Publications: Steve Scherer, Ph.D.
Selected Publications: Steve Scherer, Ph.D.
Steve Scherer, Ph.D.
Hampton, OA, Den Hollander, P, Miller, CA, Delgado, DA, Li, J, Coarfa, C, Harris, RA, Richards, S, Scherer, SE et al. A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome. Genome Res. 2008 Dec 3; . [PubMed]
Majewski, T, Lee, S, Jeong, J, Yoon, DS, Kram, A, Kim, MS, Tuziak, T, Bondaruk, J, Lee, S et al. Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy. Lab. Invest. 2008 Jul; 88(7):694-721. [PubMed]
Tribolium Genome Sequencing Consortium, Richards, S, Gibbs, RA, Weinstock, GM, Brown, SJ, Denell, R, Beeman, RW, Gibbs, R, Beeman, RW et al. The genome of the model beetle and pest Tribolium castaneum. Nature 2008 Apr 24; 452(7190):949-55. [PubMed]
Guo, DC, Pannu, H, Tran-Fadulu, V, Papke, CL, Yu, RK, Avidan, N, Bourgeois, S, Estrera, AL, Safi, HJ et al. Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections. Nat. Genet. 2007 Dec; 39(12):1488-93. [PubMed]
Pannu, H, Tran-Fadulu, V, Papke, CL, Scherer, S, Liu, Y, Presley, C, Guo, D, Estrera, AL, Safi, HJ et al. MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II. Hum. Mol. Genet. 2007 Oct 15; 16(20):2453-62. [PubMed]
Lee, S, Jeong, J, Majewski, T, Scherer, SE, Kim, MS, Tuziak, T, Tang, KS, Baggerly, K, Grossman, HB et al. Forerunner genes contiguous to RB1 contribute to the development of in situ neoplasia. Proc. Natl. Acad. Sci. U.S.A. 2007 Aug 21; 104(34):13732-7. [PubMed]
Johnson, ME, National Institute of Health Intramural Sequencing Center Comparative Sequencing Program, Cheng, Z, Morrison, VA, Scherer, S, Ventura, M, Gibbs, RA, Green, ED, Eichler, EE. Recurrent duplication-driven transposition of DNA during hominoid evolution. Proc. Natl. Acad. Sci. U.S.A. 2006 Nov 21; 103(47):17626-31. [PubMed]
Yang, Z, Bowles, NE, Scherer, SE, Taylor, MD, Kearney, DL, Ge, S, Nadvoretskiy, VV, DeFreitas, G, Carabello, B et al. Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circ. Res. 2006 Sep 15; 99(6):646-55. [PubMed]
Muzny, DM, Scherer, SE, Kaul, R, Wang, J, Yu, J, Sudbrak, R, Buhay, CJ, Chen, R, Cree, A et al. The DNA sequence, annotation and analysis of human chromosome 3. Nature 2006 Apr 27; 440(7088):1194-8. [PubMed]
Scherer, SE, Muzny, DM, Buhay, CJ, Chen, R, Cree, A, Ding, Y, Dugan-Rocha, S, Gill, R, Gunaratne, P et al. The finished DNA sequence of human chromosome 12. Nature 2006 Mar 16; 440(7082):346-51. [PubMed]
Kim, MS, Jeong, J, Majewski, T, Kram, A, Yoon, DS, Zhang, RD, Li, JZ, Ptaszynski, K, Kuang, TC et al. Evidence for alternative candidate genes near RB1 involved in clonal expansion of in situ urothelial neoplasia. Lab. Invest. 2006 Feb; 86(2):175-90. [PubMed]
Alford, RL, Morris, KE, Rives, CM, Scherer, SE, Weinstock, G, Gibbs, RA, Ghonima, K, Belcher, M, Valdes, H et al. Genetic testing, biotechnology, and GMOs: A snapshot of public opinion, 2003 through 2004. Genet. Med. ; 7(6):454-5. [PubMed]
Ross, MT, Grafham, DV, Coffey, AJ, Scherer, S, McLay, K, Muzny, D, Platzer, M, Howell, GR, Burrows, C et al. The DNA sequence of the human X chromosome. Nature 2005 Mar 17; 434(7031):325-37. [PubMed]
Richards, S, Liu, Y, Bettencourt, BR, Hradecky, P, Letovsky, S, Nielsen, R, Thornton, K, Hubisz, MJ, Chen, R et al. Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. Genome Res. 2005 Jan; 15(1):1-18. [PubMed]
Gibbs, RA, Weinstock, GM, Metzker, ML, Muzny, DM, Sodergren, EJ, Scherer, S, Scott, G, Steffen, D, Worley, KC et al. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature 2004 Apr 1; 428(6982):493-521. [PubMed]
Hasham, SN, Willing, MC, Guo, DC, Muilenburg, A, He, R, Tran, VT, Scherer, SE, Shete, SS, Milewicz, DM. Mapping a locus for familial thoracic aortic aneurysms and dissections (TAAD2) to 3p24-25. Circulation 2003 Jul 1; 107(25):3184-90. [PubMed]
Celniker, SE, Wheeler, DA, Kronmiller, B, Carlson, JW, Halpern, A, Patel, S, Adams, M, Champe, M, Dugan, SP et al. Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence. Genome Biol. 2002; 3(12):RESEARCH0079. [PubMed]
Scott, GB, Steffen, DL, Edgar, D, Warren, JT, Kovar, CL, Scherer, SE, Havlak, PH, Gibbs, RA. Loader Lite: a new software tool for the ABI PRISM 3700 DNA sequencer. BioTechniques 2002 Jun; 32(6):1366, 1368, 1370-1. [PubMed]
Chew, LJ, Yuan, X, Scherer, SE, Qie, L, Huang, F, Hayes, WP, Gallo, V. Characterization of the rat GRIK5 kainate receptor subunit gene promoter and its intragenic regions involved in neural cell specificity. J. Biol. Chem. 2001 Nov 9; 276(45):42162-71. [PubMed]
Yoon, DS, Li, L, Zhang, RD, Kram, A, Ro, JY, Johnston, D, Grossman, HB, Scherer, S, Czerniak, B. Genetic mapping and DNA sequence-based analysis of deleted regions on chromosome 16 involved in progression of bladder cancer from occult preneoplastic conditions to invasive disease. Oncogene 2001 Aug 16; 20(36):5005-14. [PubMed]
Kram, A, Li, L, Zhang, RD, Yoon, DS, Ro, JY, Johnston, D, Grossman, HB, Scherer, S, Czerniak, B. Mapping and genome sequence analysis of chromosome 5 regions involved in bladder cancer progression. Lab. Invest. 2001 Jul; 81(7):1039-48. [PubMed]
Montgomery, KT, Lee, E, Miller, A, Lau, S, Shim, C, Decker, J, Chiu, D, Emerling, S, Sekhon, M et al. A high-resolution map of human chromosome 12. Nature 2001 Feb 15; 409(6822):945-6. [PubMed]
Lander, ES, Linton, LM, Birren, B, Nusbaum, C, Zody, MC, Baldwin, J, Devon, K, Dewar, K, Doyle, M et al. Initial sequencing and analysis of the human genome. Nature 2001 Feb 15; 409(6822):860-921. [PubMed]
McPherson, JD, Marra, M, Hillier, L, Waterston, RH, Chinwalla, A, Wallis, J, Sekhon, M, Wylie, K, Mardis, ER et al. A physical map of the human genome. Nature 2001 Feb 15; 409(6822):934-41. [PubMed]
Bowles, KR, Abraham, SE, Brugada, R, Zintz, C, Comeaux, J, Sorajja, D, Tsubata, S, Li, H, Brandon, L et al. Construction of a high-resolution physical map of the chromosome 10q22-q23 dilated cardiomyopathy locus and analysis of candidate genes. Genomics 2000 Jul 15; 67(2):109-27. [PubMed]
Hoskins, RA, Nelson, CR, Berman, BP, Laverty, TR, George, RA, Ciesiolka, L, Naeemuddin, M, Arenson, AD, Durbin, J et al. A BAC-based physical map of the major autosomes of Drosophila melanogaster. Science 2000 Mar 24; 287(5461):2271-4. [PubMed]
Adams, MD, Celniker, SE, Holt, RA, Evans, CA, Gocayne, JD, Amanatides, PG, Scherer, SE, Li, PW, Hoskins, RA et al. The genome sequence of Drosophila melanogaster. Science 2000 Mar 24; 287(5461):2185-95. [PubMed]
Scherer, SE, Gallo, V. Expression and regulation of kainate and AMPA receptors in the rat neural tube. J. Neurosci. Res. 1998 May 1; 52(3):356-68. [PubMed]
Chew, LJ, Fleck, MW, Wright, P, Scherer, SE, Mayer, ML, Gallo, V. Growth factor-induced transcription of GluR1 increases functional AMPA receptor density in glial progenitor cells. J. Neurosci. 1997 Jan 1; 17(1):227-40. [PubMed]
Scherer, SE, Veres, G, Caskey, CT. The genetic structure of mouse ornithine transcarbamylase. Nucleic Acids Res. 1988 Feb 25; 16(4):1593-601. [PubMed]
Veres, G, Gibbs, RA, Scherer, SE, Caskey, CT. The molecular basis of the sparse fur mouse mutation. Science 1987 Jul 24; 237(4813):415-7. [PubMed]