Sooty Mangabey Genome Project

Image of sooty mangabey
Image source: Yerkes NPRC

Links

NCBI BioProject

About the Project

The BCM-HGSC is sequencing the genome of the sooty mangabey (Cercocebus atys). The mangabey is a model for the study of HIV infection since the simian immunodeficiency virus (SIVsmm) from sooty mangabeys is the origin of HIV-2 and sooty mangabeys infected with SIVsmm do not show clinical symptoms of disease.

Understanding these “AIDS resistance factors” in the sooty mangabey may provide insight to the biology of HIV infection and alternative strategies for the development of AIDs vaccine and prevention strateties.

The goal of the sooty mangabey genome sequencing project are to produce a high quality draft whole genome shotgun assembly. The sooty mangabey project was proposed in December 2009 in a white paper to the NHGRI.

The sequencing and comparative analysis is funded by Guido Silvestri of the University of Pennsylvania and the National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH).

Access to the Data

All sequence reads are deposited in the NCBI sequence read archive.

Assemblies of contigs and scaffolds, as well as Blast access to the data will be made available here and at the relevant public databases as soon as they are produced.

Resources

Cercocebus atys White Paper

International Genome Consortium Database

Conditions for use