Human Genome Sequencing Center, Baylor College of Medicine
 

FAQ

Why do we study animal genomes?

What other countries are participating in the HGP?

Why is Baylor College of Medicine involved in the Human Genome Project?

Which chromosomes were initially assigned to Baylor College of Medicine because of its prior research?

How much of the sequencing project will Baylor College of Medicine complete?

 

Q: Why do we study animal genomes?
A: Scientists study and compare animal genomes to discover new knowledge about human biology and to understand the relationships among all of the diverse forms of life on earth. The order of chemical bases (A,T, C, G) in a genome is extremely important. The specific order determines if you are another species, such as a fruit fly or a mouse. All species have similarities in their DNA sequences that are important markers for biological research. What happens when the human genome is completed? Although the completed sequence in 2003 will represent an enormous scientific achievement, much work remains to realize the full potential of this accomplishment. Early explorations into the human genome, now joined by projects on the genomes of dozens of other organisms, are generating data whose volume and complex analyses are unprecedented in biology. Deriving meaningful knowledge from DNA sequence will define biological research through the coming decades and require the expertise and creativity of teams of biologists, chemists, engineers, and computational scientists.
 
Q: What other countries are participating in the HGP?
A: At least 18 other countries have established human genome research programs. Some of the larger programs are in Australia, Brazil, Canada, China, Denmark, European Union, France, Germany, Israel, Italy, Japan, Korea, Mexico, Netherlands, Russia, Sweden, United Kingdom and the United States. Some developing countries are participating through studies of molecular biology techniques that are particularly interesting to their region. The Human Genome Organization helps to coordinate international collaboration in the Human Genome Project.
 
Q: Why is Baylor College of Medicine involved in the Human Genome Project?
A: Baylor College of Medicine began its research in the fields of genetics and molecular biology more than 20 years ago, as the field was beginning. BCM has been the site of many important genetic discoveries, including the genes for Fragile X syndrome, muscular dystrophy, types of nuerodegenerative disorders including spinocerebellar ataxia type 1 and Charcot Marie Tooth Syndrome. Baylor College of Medicine was one of the three centers that successfully completed the HGP pilot project phase and was therefore selected as one of the three NHGRI funded centers to scale-up and complete the final push to sequence the human genome.
 
Q: Which chromosomes were initially assigned to Baylor College of Medicine because of its prior research?
A: Chromosomes 3, 12, and X
 
Q: How much of the sequencing project will Baylor College of Medicine complete?
A: Baylor will complete about 10% of the human genome
 
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