Androgen receptor CAG repeat polymorphism in males of six non-human primate species.

Title	Androgen receptor CAG repeat polymorphism in males of six non-human primate species.
Publication Type	Journal Article
Year of Publication	2012
Authors	Mubiru, JN, Cavazos, N, Hemmat, P, Garcia-Forey, M, Shade, RE, Rogers, J
Journal	J Med Primatol
Volume	41
Issue	1
Pagination	67-70
Date Published	2012 Feb
ISSN	1600-0684
Keywords	Animals, DNA, Male, Pan troglodytes, Polymerase Chain Reaction, Polymorphism, Genetic, Primates, Receptors, Androgen, Trinucleotide Repeats
Abstract	BACKGROUND: Androgen receptor [CAG](n) microsatellite has been linked to human diseases.METHODS: Six non-human primates were genotyped for the [CAG](n) microsatellite.RESULTS: Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic.CONCLUSIONS: Non-human primates that are polymorphic for the microsatellite are candidate animal models for CAG-related diseases.
DOI	10.1111/j.1600-0684.2011.00517.x
Alternate Journal	J Med Primatol
PubMed ID	21978295
PubMed Central ID	PMC3479659
Grant List	K01 RR025161 / RR / NCRR NIH HHS / United States K01RR025161-01 / RR / NCRR NIH HHS / United States RR013556 / RR / NCRR NIH HHS / United States C06 RR013556 / RR / NCRR NIH HHS / United States K01 OD010973 / OD / NIH HHS / United States P51 RR0139986 / RR / NCRR NIH HHS / United States P51 RR013986 / RR / NCRR NIH HHS / United States