Title | Transcriptome of Treponema pallidum: gene expression profile during experimental rabbit infection. |
Publication Type | Journal Article |
Year of Publication | 2005 |
Authors | Smajs, D, McKevitt, M, Howell, JK, Norris, SJ, Cai, W-W, Palzkill, T, Weinstock, GM |
Journal | J Bacteriol |
Volume | 187 |
Issue | 5 |
Pagination | 1866-74 |
Date Published | 2005 Mar |
ISSN | 0021-9193 |
Keywords | Animals, Gene Expression, Gene Expression Profiling, Oligonucleotide Array Sequence Analysis, Open Reading Frames, Rabbits, RNA, Bacterial, RNA, Messenger, Syphilis, Treponema pallidum |
Abstract | RNA transcript levels in the syphilis spirochete Treponema pallidum subsp. pallidum (Nichols) isolated from experimentally infected rabbits were determined by the use of DNA microarray technology. This characterization of the T. pallidum transcriptome during experimental infection provides further insight into the importance of gene expression levels for the survival and pathogenesis of this bacterium. |
DOI | 10.1128/JB.187.5.1866-1874.2005 |
Alternate Journal | J Bacteriol |
PubMed ID | 15716460 |
PubMed Central ID | PMC1063989 |
Grant List | R01 AI045842 / AI / NIAID NIH HHS / United States R01 DA013759 / DA / NIDA NIH HHS / United States AI45842 / AI / NIAID NIH HHS / United States R01 AI049252 / AI / NIAID NIH HHS / United States R01 AI49252 / AI / NIAID NIH HHS / United States R01 DE12488 / DE / NIDCR NIH HHS / United States R01 DE13759 / DE / NIDCR NIH HHS / United States R01 EY013759 / EY / NEI NIH HHS / United States |
Transcriptome of Treponema pallidum: gene expression profile during experimental rabbit infection.
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